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标题: 为什么要给种公补充辅酶Q10?——GTG犬类健康系列 [打印本页]

作者: 晨光    时间: 2009-11-13 19:51
标题: 为什么要给种公补充辅酶Q10?——GTG犬类健康系列
作为一名繁殖者,我们应该在事先考虑清楚母犬的健康状况,以及它繁殖幼犬的能力。然而往往由于这一点,我们有时似乎会忽略种公在这些问题上的责任。毕竟,种公也在繁殖上占有一半的任务,如果幼犬不符合繁殖标准,那就是种公的责任了。(是的,确实带点讽刺的意味。)



大多数人认为一窝幼犬如果数量很少,其原因要么是母犬本身就只能生那么多,要么就是母犬的母亲也只生了两只小狗,因而对它就没有抱过高的期望。我们的观点是基于以往的经验,而并没有考虑到后面繁殖出的幼犬的各种情况。但当我们不惜重金,将母犬漂洋过海地与种公进行交配,却又从不询问公犬的主人有关它的生殖能力相关的问题时,我们发现关注繁殖出幼犬似乎更为关键。我们是不是应该了解与种公配种的母犬每次能产出多少幼犬?近期它又与几只母犬交配过?交配频繁不等于就能高产精子。实际上,反而会更少。作为公犬的主人,我们同样要对犬只的适用性及其生殖能力负责。

公犬与一整窝幼犬的体型有关,这不仅是靠精子密度(精子数)来得以实现,还要看精子的运动性(精子移动),包括精子形态。这可能取决于精子的实际结构,例如犬只尾巴的长度和形状,或是头版的大小。以上提到的三个部分,连同良好的身体条件和活力值,将有助于产出体型较大的幼犬。精子游向卵子的能力取决于它克服周围障碍的能力,比如,母犬阴道内PH值,或是分泌物的黏度。根据以上这些信息,我们就可以了解到光有精子量是远远不够的,还必须要有足够的活跃度,才能完成最终的目标。

其中一个亟待解答的问题是,我们能否提高精子的密度,运动性,形态,延长种公的繁殖能力,以帮助我们达到繁殖的目的?问题的答案无疑是肯定的。一个很简单的解决方案是在犬只的晚餐中添加辅酶Q10。六周内,犬只的生殖器官4个区域的性能都有所提高。包括年纪大的种公。研究人员先对犬只进行试验,然后将其运用于人体实验,反映出对人类也有同样的效用,所以当你在阅读这篇文章时,会很容易将自己置身于犬类的世界中。

辅酶Q10可以被称作为一种维生素,或者说是类似维生素类的物质;目前研究者们对这一物质在生物科学中的系统命名尚存在分歧。众所周之,它是一种脂溶性物质,是生物体、犬只或是人类细胞所含有且必需的。简言之,辅酶Q10参与“有氧细胞的呼吸作用”(激活细胞呼吸及活动,加速产生所需的“能量”),生成储存能量的主要因子ATP(三磷酸腺苷)。对所有想获得肾上腺素的人来说,在训练过程中,ATP最快速最直接的来源是肌肉。“ATP”第一波能量被称作“对抗或逃避反应”,只存在于有辅酶Q10的环境中。同样,在使用精子前,存在于精液之中。辅酶Q10还是“电子传输链”的重要组成元素(将信息输送到所有细胞)。研究表明,物种中95%的能量源于这样的传输方式。我们要谨记,能量输出最大化的途径之一是分娩的过程,因此,总的来说,辅酶Q10是运动消耗所必需的。心脏和肝脏是每日消耗能量最大的器官,巧合的是,研究显示,这些器官正是辅酶Q10最为集中的区域。如果另一个角度看,在患有代谢性疾病的人与犬类中,都会发现他们缺乏相同数量的辅酶Q10。此外,在首先对犬,其次是人类的研究表明,当步入老年时,体内的辅酶Q10会逐渐减少,机体便要负担老化过程,减缓身体所有部位的功能。这项研究已经根据“生物能学”进行,如上所述,它是专门针对细胞能量及再生的研究。现在,那些为人类及犬类寻求“青春之泉”的研究者正向与“自由基化学”相关的周边领域发展。令人欣喜的是,经过研究,辅酶Q10已经作为一种有效的抗氧化剂来缓解老化过程,并通过抑制损害细胞的自由基以延缓多种类型的癌症。

目前一直有许多利用治疗性辅酶Q10的研究,并对它们对病症的影响及效果进行相关记录。这其中包括一些对如深海自由潜水运动员运动成绩的研究。他们下潜的深度是我们难以想象的。日本是第一个让女人进行潜水的国家,她们潜水时为了获取珍珠。这是在浅水区内完成的,但是潜水者要花费很长的时间。(请注意,日本是世界上最缺少辅酶Q10的国家。)辅酶Q10的主要功能是呼吸,肺活量的表现是我们肉眼所能看到的最直观的细胞水平的运作情况。目前正在进行辅酶Q10对有关疲劳,解压以及各型心脏疾病所起作用的研究,它能减缓,甚至能抵御各种损伤心脏或是导致心脏衰竭的疾病,一些研究表明,如果病人在治疗期间服用适量的辅酶Q10,那么在接受如冠状动脉搭桥的大手术后,其功能的恢复能力将有所提升。请记住,许多相关的研究都始于犬类,然后才应用于人类。使用辅酶Q10还可以有效避免偏头痛,或是显著减少慢性患者。对犬类而言,往往存在牙龈疾病及严重的牙结石问题。而辅酶Q10能修复牙龈组织,减少牙齿掉落产生的影响。最后也是最重要的一点是,辅酶Q10与高胆固醇水平似乎有着相关性。那些带有辅酶Q10的正常血清中胆固醇水平较低,而高胆固醇则出现在含辅酶Q10偏低的血清中。在临床上找到验证的一种简便方法就是请你的健康护理员对你或犬做一项血液测试,寻求解决方案。综上所述,在国内(美国)或是其他国家,都资助进行这些研究。目前,我们(指美国)提供世界上超过80%的有关辅酶Q10研究的基金。

有关辅酶Q10的研究历史并不长,Crane博士于1957年在牛心脏中找到辅酶Q10。1958年,默克公司成功绘制出了首张辅酶Q10的化学分子结构图。而后六十年代中期,在日本,有教授首次使用被称为辅酶Q7的相关化合物,用于治疗充血性心力衰竭。后来,在七十年代,研究人员对患病心脏内辅酶Q10缺失有相关记载。日本人完善了这项技术,他们生产大量的辅酶Q10,以用于临床试验。1978年,美国人Peter Mitchell因其对辅酶Q10“能量转移系统”的贡献而荣获诺贝尔奖。之后,对这种神奇的“维生素”的研究在日本,德国,美国,瑞典等国家迅速波及开来,他们的研究成果在走在世界前列。有趣的是,现在美国所有可用的辅酶Q10都是由日本生产,然后分派给美国的不同医药公司,制成片剂,胶囊或分装液体。大部分辅酶Q10来自鱼类,海藻或海带。

在你在给犬喂食营养全面的犬类食品中,有些食物含有高密度的辅酶Q10的,如内脏器官,象心,肝,肾等,此外,还包括沙丁鱼,鲭鱼,牛肉和花生。考虑到辅酶Q10,我总是选择那些能给犬提供全面营养的食物,例如沙丁鱼。它能让所有维生素,矿物质以及必需脂肪酸都将辅酶Q10的运用效果达到最大化。辅酶Q10的形成需要有至少七种合成维生素的作用,它们分别是B2-核黄素,B3-烟酰胺,B6,B12,叶酸,维生素C以及泛酸。大多数食物中都含有上述七种维生素。由于辅酶Q10被列入“安全”类药品(意思就是无毒,无副作用),我也推荐使用胶囊或是液体状药剂,来作为犬类的营养补充剂。当你在查看产品标签,看看要买哪一种时,你可以考虑哪些添加维生素E和维生素B群的辅酶Q10产品。液态的容易储存,因为大部分产品不需要另藏,只要放置于阴凉通风处且方便取用即可。需要提醒的一点是,该产品一般为亮橙色稠状物,因此我建议在喂食赛级犬时,可以再面包上蘸一点,作为它吃饭时的奖赏。至于需要给犬服用多少剂量,则根据其他营养食品的使用量而定。如果你已经喂食鱼类,如沙丁鱼,鲭鱼,鲱鱼或是鲑鱼,那就不需要添加任何东西了。但如若犬粮中没有鱼类,那小型犬可添加10㎎,中型犬添加30㎎,大型犬则为60㎎。

翻译:卡卡
作者: 晨光    时间: 2009-11-13 19:52
原文:

As a breeder, concern for the bitches health and ability to whelp a litter of pups is usually forward thinking when working through issues. To this end we, at times, seem to neglect the stud dog in sharing dog issues. After all, a dog at stud just does his half and it is only his fault if the puppies do not fit the breed standard (yes, I am being cynical).
There seems to be a consensus that a small litter is due to the bitch having small litters, or her mother only had two pups in her litters, so there is no further expectation. Our thinking is based on past experiences instead considering the possibilities for future litters. It seems to make more sense to work through the latter half of the previous statement, as we incur great expenses in shipping our champion bitches cross country to engage the best stud without ever asking the stud owner about the health and the dog’s virility. Should we be asking how many pups per litter he has produced and how many bitches he serviced in the last year? Use does not equal higher sperm count and, in fact, could mean less. As stud owners, we need to take responsibility for the usability and vitality of our dogs.
The stud dog has responsibilities in litter size, this end is accomplished not only in the density of sperm (sperm count), but in the motility of the sperm (the sperm movement), including the morphology. This would be the actual structure of the sperm, such as the length and shape of the tail or size of head. These three issues together with good health and vitality would help to produce a larger litter. The ability for the sperm to travel to the released egg depends upon its ability to overcome obstacles of environment such as the PH and viscosity (thickness) of fluid within the bitches’ vagina. With this information you can understand how important it is to not only have a greater sperm count but to have healthy vigorous sperm to obtain this goal.
One of the questions needing an answer is can we increase density, motility and morphology of the sperm, as well as the ability to handle the rigors of standing at stud, to aid in our goal of reproduction? The answer to this question is yes. A very simple solution in adding COENZYME Q 10 to the evening meal. This will help with all 4 areas of virility in less than 6 weeks and this includes stud dogs that are older, too. Research was done with dogs first and then humans and it was done for the benefit of humans, so while reading this you may easily insert yourself in the place of the word dog.
COENZYME Q 10 can be described as a vitamin or perhaps more as a vitamin-like substance; there are disagreements amongst the researchers about where this should fit in the nomenclature of bioscience. It is known to be a fat-soluble substance that is present and needed in every cell of the body, dog or human. In the shortest way of explaining this, it is a participant in “aerobic cellular respiration” (that which causes breath and activity at the cell level and being “energy”), generating energy in the form of “ATP”. For all of you who work out or get adrenalin kicks, this is for the fastest energy coming straight from the muscle during workouts. “ATP” is the first energy called upon for “flight or fight”, and is only available if you have COENZYME Q 10 to produce this before the need. The same goes for the production of sperm before you need the use of the sperm. COENZYME Q 10 is also one of the main components of the “electron transport chain” (messages sent to all of the cells). Research has shown that 95% of any species energy is generated this way. We need to remember that one of the greatest energy outputs is accomplished in reproduction, therefore drawing the conclusion that COENZYME Q 10 is required for this activity in the greatest amount. The organs that use the greatest energy on a daily basis would be the heart and the liver and coincidentally research has found the greatest concentrations of COENZYME Q 10 in these organs. If you look at the opposite side of the coin, it has been shown that in humans and dogs with metabolic disorders you find equally deficient amounts of COENZYME Q 10 accounted for. There also has been research done on dogs first and then humans that as we age we have less COENZYME Q 10 in our bodies and thusly affording the aging process to take place and slowing down all portions of the body. This research has taken place under the term “Bioenergetics” and, as stated, it is the study that specifically researches cell energy and its production. Now for those of you looking for the “fountain of youth” for you or your canine charges it skirts on the related field of “free radical chemistry”. COQ10 has been studied with impressive results as a potent antioxidant that lends itself to reversing the aging process as well as staving off many forms of cancer by neutralizing the free radicals that cause damage to cells.
There have been many studies using therapeutic amounts of COQ10 and documenting their effects on the maladies they affect. This includes some research on athletic performance including deep free diving athletes. These people dive to depths beyond your imagination. Japan was the first to send women underwater diving for pearls. This is done in shallower waters but uses extended dive times. (please note the Japan has fewer issues with COQ10 deficiencies than anywhere else in the world.) Remember that COQ10s’ main function is respiration and that lung capacity gives us the best visual in the macro image of things as to how it works at the cellular level. There is ongoing research in the area of fatigue and recovery from stress as well as the dynamics of every type of heart disease and how the use of COENZYME Q 10 can slow or even reverse many different types of damage to the heart as well as heart failure to the point that several studies have suggested that the function of the heart improves after major surgery such as coronary artery bypass if the patient is given therapeutic amounts of COQ10. Remember that many of these research studies started off with dogs and progressed to humans. Migraine headaches have been prevented with use of COQ10 and/or diminished significantly for chronic sufferers. For dogs that have gum disease and excessive tarter, COQ10 has supported the gum tissue and reversed the effects of tooth loss. Last but not least there seems to be a correlation between levels of COENZYME Q 10 and high cholesterol. Those with good blood serum levels of COQ10 have lower cholesterol and those with high cholesterol levels have low blood serum levels. An easy way of finding this information on a clinical level is to get a blood test done by your health care provider for you or your dog and determine a course of action. With all of the above there is ongoing research that is funded by the USA for research within the USA and abroad. We (the USA) currently fund more than 80% of all ongoing research on COENZYME Q 10 around the world.
As for a short history of COENZYME Q 10, Dr. Crane isolated the very first finding of COENZYME Q 10 in beef heart in 1957. In 1958 Merck, Inc. was able to map the first chemical structure of COQ10. Then, in Japan, in the mid-’60s a professor was the first in the world to use a related compound called COENZYME Q 7 to treat congestive heart failure. Later in the ‘70s researchers were documenting deficiencies of COQ10 in the human heart that was diseased. It was the Japanese that perfected the technology to produce quantities of COQ10 that supported large clinical trials. Then in 1978 it was the American Peter Mitchell who received the Nobel Prize for his contribution to the understanding of the need for COQ10 in the “energy transfer system”. After that the research on this amazing “vitamin” accelerated around the world with countries like Japan, Germany, the USA and Sweden taking the lead in research. It is interesting to note that all COENZYME Q 10 available today in the USA is manufactured in Japan and then distributed to companies in the USA who make it into tablets, capsules and liquids. Much of the COQ10 comes from fish and seaweed, or in kelp form.
When you are feeding whole foods to your dog, there are certain foods that have a higher density level of COENZYME Q 10. Some of these foods would be organ meats such as heart, liver and kidney, as well as sardines, mackerel, beef, and peanuts. With COENZYME Q 10, my preference would always be to eat whole foods so as to allow the dog to use everything within concert, such as a sardine. This will already have all the vitamins and minerals and essential fatty acids to allow the use of COQ10 at its greatest level. COENZYME Q 10 has shown to need at least 7 vitamins for the biosynthesis to occur. These are B2 - riboflavin, B3 – niacin amide, B6, B12, folic acid, C and pantothenic acid. Most foods that are eaten will have all the needed vitamins. Since COENZYMEQ 10 is listed as a “safe” (meaning that it is not-toxic and does not have side effects), I would also recommend using the supplemented forms that come in gel caps and/or liquid. When reading your labels to see which one to purchase, you can look for those COENZYME Q10 products that add Vitamin E and the B’s. The liquid is easy to keep, as most of the products do not need refrigeration, just storage in a cool dark place, and with a pump to make it easy to dispense. One word of caution, this product is generally bright orange in color and sticky, so for a show dog in coat I would advise to squirt a little on bread and give it as a treat with a meal. When deciding how much to give to your dog, it would depend on what other additives are being given. If you are already giving fish such as sardine, mackerel, herring, or salmon you may not need to add anything at all. If you are not adding fish regularly you would add 10mg for a small breed dog and 30mg for a medium breed dog and up to 60mg for large breeds.




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